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Guys I have several Tapentadol pills (50 mg ER) Does it have any recreational value? How does it compare to Tramadol? Any experiences? I love trams, but I'm very afraid of seizure risks Perhaps Tapentadol being a stronger opioid (compared to Tramadol), does not need such a high dose to use Hey magicblack! Your question's a pretty easy one, so let's do it Basically, Tapendatol (Nucynta) is an Opioid It also is a Norepinephrine Reuptake Inhibitor (NRI), which will give it some effects that differentiate it from other "standard" Opioid agonists, but the main takeaway is that Tapentadol is a fairly potent Opioid agonist and thus produces respiratory depression in high doses It Tapentadol is an opioid and differs from opiates (drugs that metabolize into morphine) such as Codeine and Hydrocodone Tapentadol does not have any known active metabolites, unlike opiates and Tramadol Tramadol is however, quite similar to Tapentadol , in that it has a dual mechanism of action in that acts at the same receptor sites Feb 24, 2009 · Unlike most opioids, tapentadol is also a norepinephrine reuptake inhibitor and also has weak serotonergic effects as well Tapentadol is an orally available, synthetic benzenoid that acts as an agonist for the mu-opioid receptor (MOR) and inhibits the reuptake of noradrenaline, with potential anti-nociceptive activity Unlike most opioids, tapentadol is also a norepinephrine reuptake inhibitor and also has weak serotonergic effects as well Tapentadol is an orally available, synthetic benzenoid that acts as an agonist for the mu-opioid receptor (MOR) and inhibits the reuptake of noradrenaline, with potential anti-nociceptive activity DISCLAIMER: I have not tried these specific pills nor Soma Carisoprodol in general Have done a lot of Tapentadol though tapentadol definitely responds well to redose in my experience, that shouldn't be an issue at all your concern about mixing two CNS depressants especially as someone with no real opiate tolerance is extremely valid and reasonable, I think it's wise to try one pill at a Hello, I’ve High opioid tolerance I’ve just got some tapentadol (extended release) and no sure how they work, can I crush them for immediate release, what’s the most I can take in a day? (I’m used to Tramadol and 15x DHC -30 mg all in one go Please help!!!What dose of Tapentadol have you found effective? Is it similiar in potency to Oxycodone? ThanksDec 10, 2017 · What dose of Tapentadol have you found effective? Is it similiar in potency to Oxycodone? Thanks Drug : Tapentadol Brand : Palexis Retard (aka Palexia Retard) - Extended Release Formulation Dose : 300 mg Route of Administration : Oral About Me : Low to Medium-Tolerance to Opioids (I had only taken tramadol, tapentadol codeine, and buprenorphine )Nov 15, 2010 · The only negative with Tapentadol , sometimes, would be that it makes me sleepier and there is a definite nod phase which is not there in Tramadol I have not tried Hydrocodone but I would agree that Tapentadol is on par with Morphine (not on a per mg basis, Morphine in my experience was 2-3 times as potent on that level) --- bluelight org tapentadol-palexia-retard-retrospective-underrated-opio --- bluelight org community threads page-2Oct 27, 2014 · DISCLAIMER: I have not tried these specific pills nor Soma Carisoprodol in general Have done a lot of Tapentadol though tapentadol definitely responds well to redose in my experience, that shouldn't be an issue at all your concern about mixing two CNS depressants especially as someone with no real opiate tolerance is extremely valid and reasonable, I think it's wise to try one pill at a --- bluelight org community threads tapentadol-megathread 920933--- bluelight org community what-dose-of-tapentadol-have-you-taken 917284Tapentadol is an opioid and differs from opiates (drugs that metabolize into morphine) such as Codeine and Hydrocodone Tapentadol does not have any known active metabolites, unlike opiates and Tramadol Tramadol is however, quite similar to Tapentadol, in that it has a dual mechanism of action in that acts at the same receptor sites Nov 23, 2019 · Guys I have several Tapentadol pills (50 mg ER) Does it have any recreational value? How does it compare to Tramadol? Any experiences? I love trams, but I'm very afraid of seizure risks Perhaps Tapentadol being a stronger opioid (compared to Tramadol), does not need such a high dose to use --- bluelight org community threads tapentadol-withdrawal 917293The only negative with Tapentadol, sometimes, would be that it makes me sleepier and there is a definite nod phase which is not there in Tramadol I have not tried Hydrocodone but I would agree that Tapentadol is on par with Morphine (not on a per mg basis, Morphine in my experience was 2-3 times as potent on that level) --- bluelight org community threads tapentadol 861394--- bluelight org community threads tapentadol-or-tramadol 920667Apr 26, 2021 · Hello, I’ve High opioid tolerance I’ve just got some tapentadol (extended release) and no sure how they work, can I crush them for immediate release, what’s the most I can take in a day? (I’m used to Tramadol and 15x DHC -30 mg all in one go Please help!!! --- bluelight org red-apple-pills-tapentadol-carisoprodol-anyone-done-the Aug 8, 2021 · Same goes for tapentadol , but I don't have any experience with tapentadol so i'm not sure how different it is from tramadol in subjective effects If you plan on taking doses over 300-400mg per day of tramadol or are prone to seizures, be very cautious when taking either tapentadol or tramadol --- bluelight org community threads tapentadol 901307Dec 8, 2020 · Drug : Tapentadol Brand : Palexis Retard (aka Palexia Retard) - Extended Release Formulation Dose : 300 mg Route of Administration : Oral About Me : Low to Medium-Tolerance to Opioids (I had only taken tramadol, tapentadol codeine, and buprenorphine ) --- bluelight org community threads tapentadol-vs-tramadol 881159Same goes for tapentadol, but I don't have any experience with tapentadol so i'm not sure how different it is from tramadol in subjective effects If you plan on taking doses over 300-400mg per day of tramadol or are prone to seizures, be very cautious when taking either tapentadol or tramadol Jan 11, 2019 · Hey magicblack! Your question's a pretty easy one, so let's do it Basically, Tapendatol (Nucynta) is an Opioid It also is a Norepinephrine Reuptake Inhibitor (NRI), which will give it some effects that differentiate it from other "standard" Opioid agonists, but the main takeaway is that Tapentadol is a fairly potent Opioid agonist and thus produces respiratory depression in high doses It


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